Here is how to watch all Major League Soccer matches live in Week 21 on TV or streaming. You can follow along with our live scores and stats throughout the weekend as well.
Saturday, July 21
| TIME(EST) | TEAM | TV | Live stream |
| 3:30 p.m. | Atlanta v DC United | USA: Univision, Univision Deportes Network, Twitter (ENG audio) | CAN: MLS LIVE on DAZN |
| 4 p.m. | Seattle v Vancouver | SEA: JOEtv, YouTube TV [Seattle region only]; CAN: TSN1 | ESPN+, Direct Kick |
| 7 p.m. | Chicago v Toronto | CHI:ESPN+; CAN: TSN 1/4 | ESPN+, Direct Kick |
| 7 p.m. | NY Red Bulls v New England | RBNY:MSG; NE: NBC Sports Boston | ESPN+, Direct Kick, MLS LIVE on DAZN |
| 7 p.m. | Philadelphia v LA Galaxy | PHI: PHL17; LA:Spectrum SportsNet | ESPN+, Direct Kick, MLS LIVE on DAZN |
| 7:30 p.m. | Columbus v Orlando City | CLB: CW Columbus, Spectrum Sports OH, BCSN2; ORL: TV27, YouTube TV [Orlando only] | ESPN+, Direct Kick, MLS LIVE on DAZN |
| 9 p.m. | Houston v FC Dallas | HOU: KUBE57; DAL: TXA-21 | ESPN+, Direct Kick, MLS LIVE on DAZN |
| 10 p.m. | Real Salt Lake v Colorado | RSL: KMYU; COL: Altitude | ESPN+, Direct Kick, MLS LIVE on DAZN |
| 11 p.m. | Portland v Montreal | POR: KPTV (FOX 12); CAN: TVAS | ESPN+, Direct Kick |
Sunday, July 22
| TIME(EST) | TEAM | TV | Live stream |
| 7 p.m. | Minnesota v LAFC | MIN: FOX Sports North; LA: YouTube TV [LA region only], UniMás 46; CAN: TSN2 | ESPN+, Direct Kick |